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Lifestyle factors and underlying medical conditions are associated with an increased risk of community-acquired pneumonia


Community-acquired pneumonia ( CAP ) causes considerable morbidity and mortality in adults, particularly in the elderly.

Structured searches of PubMed were conducted to identify up-to-date information on the incidence of community-acquired pneumonia in adults in Europe, as well as data on lifestyle and medical risk factors for community-acquired pneumonia.

The overall annual incidence of community-acquired pneumonia in adults ranged between 1.07 to 1.2 per 1000 person-years and 1.54 to 1.7 per 1000 population and increased with age ( 14 per 1000 person-years in adults aged greater than or equal to 65 years ).

Incidence was also higher in men than in women and in patients with chronic respiratory disease or HIV infection.

Lifestyle factors associated with an increased risk of community-acquired pneumonia included smoking, alcohol abuse, being underweight, having regular contact with children and poor dental hygiene.

The presence of comorbid conditions, including chronic respiratory and cardiovascular diseases, cerebrovascular disease, Parkinson's disease, epilepsy, dementia, dysphagia, HIV or chronic renal or liver disease all increased the risk of community-acquired pneumonia by twofold to fourfold.

In conclusion, a range of lifestyle factors and underlying medical conditions are associated with an increased risk of community-acquired pneumonia in European adults.
Understanding of the types of individual at greatest risk of community-acquired pneumonia can help to ensure that interventions to reduce the risk of infection and burden of disease are targeted appropriately. ( Xagena )

Torres A et al, Thorax 2013;68:1057-1065

XagenaMedicine_2015



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