PulmonologyNews.net

Pulmonology Xagena

Xagena Mappa
Medical Meeting
XagenaNewsletter
Ematobase.it

Decreased physical performance due to loss of muscle mass ( i.e. sarcopenia ) is prevalent in ageing and appears more pronounced in chronic disease. A comprehensive profile of the sarcopenic phenotype ...


The safety and efficacy of adding Bosentan ( Tracleer ) to Sildenafil ( Revatio ) in pulmonary arterial hypertension ( PAH ) patients was investigated. In this prospective, double-blind, event-driv ...


MicroRNAs ( miRNAs ) are endogenous small ( 19-24 nt long ) noncoding RNAs that regulate gene expression in a sequence specific manner. An increasing association between miRNA and cancer has been re ...


mTOR inhibitors have clinically significant activity against various malignancies, such as renal cell carcinoma and breast cancer, but their use can be complicated by several toxicities. Interstitia ...


Epidermal growth factor receptor-tyrosine kinase inhibitors ( EGFR-TKIs ) are a critical member of systemic therapy for advanced non-small-cell lung cancer ( NSCLC ). Erlotinib ( Tarceva ) is the ...


In the two replicate, placebo-controlled, 52-week, phase III INPULSIS trials, Nintedanib ( Ofev ) 150 mg twice daily significantly reduced the annual rate of decline in forced vital capacity ( FVC ), ...


The role of Tiotropium ( Spiriva ) for the treatment of adolescents with asthma has not yet been clearly defined. A study has assessed the efficacy and safety of inhaled Tiotropium in adolescents with ...


Data were reported from across AstraZeneca’s industry-leading lung cancer portfolio at the World Conference on Lung Cancer ( WCLC ) 2015, in Denver, Colorado ( U.S. ). 25 abstracts ( including 9 oral ...


Community-acquired pneumonia ( CAP ) causes considerable morbidity and mortality in adults, particularly in the elderly. Structured searches of PubMed were conducted to identify up-to-date informat ...


Idiopathic pulmonary fibrosis ( IPF ) is a progressive disease characterised by dyspnea and loss of lung function. Using pooled data from the replicate, randomized, 52-week, placebo-controlled INPU ...


Alectinib ( Alecensa ) is a second-generation, orally active, potent and highly selective inhibitor of anaplastic lymphoma kinase ( ALK ). Alectinib is approved for the treatment of ALK fusion-gen ...


Lung cancer patients with comorbid conditions such as chronic obstructive pulmonary disease ( COPD ), diabetes mellitus, or congestive heart failure had a higher risk of death than lung cancer patient ...


The maturation, recruitment and survival of eosinophils in the respiratory tract are determined by IL-3, GM-CSF, but especially by IL-5, which has a key role in mediating airways eosinophilic inflamma ...


Additional results from an interim analysis of a pivotal phase 2b study of Dupilumab in adult patients with moderate-to-severe asthma who are uncontrolled despite treatment with inhaled corticosteroid ...


A study has investigated the effects on 24-h lung function and lung volume of a once-daily fixed-dose combination ( FDC ) of the long-acting muscarinic antagonist Tiotropium and the long-acting beta2- ...